in addition, apr is also used in the field of health-care products and cosmetics. a. biserrata and a. pubescens both belong to the genus angelica of the family apiaceae, and the former is a variant of the latter. the application of apr in the field of health care has a long history. in addition, they are known to possess a myriad of pharmacological activities, including antioxidant, anti-cancer, and anticoagulant effects. the chemical structures of the steroids are shown in figure 3. apart from the ingredients above, other compounds have been isolated and identified from a. biserrata and a. pubescens. the anti-inflammatory and analgesic constituents from a. pubescens appear to be related to the peripheral inhibition of inflammatory substances and to have influences on the central nervous system (chen et al., 1995). finally, apr has a regulating effect on immune inflammatory injury in ad and vd rats, particularly for the treatment of vd (wang et al., 2011a). the alcohol extract of rab (arab) and wrab both have anti-angiogenic effects (zou et al., 2008; hu et al., 2013b). the main pharmacokinetic researches of the extracts or isolated compounds from apr that have been reported studies in animal are discussed below. for tissue distribution, the amount of bisabolangelone (80) mainly appeared in heart, liver and spleen. no differences in the blood and biochemistry indexes of rats and dogs were observed (duan et al., 2002). a significant breakthrough has been made in the last several decades in the areas of phytochemistry and pharmacology of apr. in order to standardize the use of traditional chinese medicine, it is necessary to study the specific differences in the clinical use and pharmacological effect of the two medicinal plants. zw and lt contributed comments for a version of the manuscript. studies on coumarins from the root of angelica pubescens maxim. anti-inflammatory and analgesic activities from roots of angelica pubescens. studies on the constituents of coumarins from duhuo. the research on acute and long-time toxicity of angelicaroot capsule. pharmacokinetics and tissue distribution study of bisabolangelone from angelicae pubescentis radix in rat using lc–ms/ms. the constitution of angelol, a new coumarin isolated from the root of angelica pubescens maxim (umbelliferae). experimental study of angelica pubescens and osthole isolated from angelica pubescens inhibiting angiogenesis in vitro. the neuroprotective effect of total coumarins of angelica pubescentis on app/ps1 double transgenic ad model mouse.
the pharmacokinetics, bioavailability and excretion of columbianetin acetate and its metabolite columbianetin were analysed in rat plasma by lc-ms/ms after administration of columbianetin acetate and angelicae pubescentis radix extract. studies on coumarins from the root of angelica pubescens maxim. analgesic effect of coumarins from radix angelicae pubescentis is mediated by inflammatory factors and trpv1 in a spared nerve injury model of neuropathic pain. simultaneous determination of columbianadin and its metabolite columbianetin in rat plasma by lc-ms/ms: application to pharmacokinetics of columbianadin after oral administration. studies on the chemical constituents of angelica pubescens f. biserrata and its anti-human platelet and anti-inflammatory effects. studies of nmr and ms on 6- or 8-alkyl-7-oxycoumarins and dihydrofuranocoumarins. the pharmacokinetics and oral bioavailability studies of columbianetin in rats after oral and intravenous administration. isolation and identification of isoangelol, anpubesol and other coumarins from angelica pubescens maxin. effects of duhuo and its alcohol extracts on apoptosis of brain tissue in natural aging mice. j. chin. experimental study on the regulation of il-4 and tnf-α in rats with ad and vd by chinese medicine duhuo. anthelmintic activity of the crude extracts, fractions, and osthole from radix angelicae pubescentis against dactylogyrus intermedius in goldfish (carassius auratus) in vivo. quantitative analysis of ca, mg, and k in the roots of angelica pubescens f. biserrata by laser-induced breakdown spectroscopy combined with artificial neural networks. effects of four herbal extracts on adjuvant-induced inflammation and hyperalgesia in rats. study on the active site and extraction method of duhuo in killing dioscorea japonicus. j. chin. novel coumarin and furan from the roots of angelica pubescens f. biserrata. distribution assessments of coumarins from angelicae pubescentis radix in rat cerebrospinal fluid and brain by liquid chromatography tandem mass spectrometry analysis. exploration and analysis on the potential function of radix angelicae pubescentis. j. chin. the experimental study of the intervention effect of duhuo on immune damage of model rats suffering from alzheimer. experimental study on antiangiogenic effect of duhuo. the use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice.
dong quai has anticoagulant and antiplatelet activities and appears to require the synergism of other plants for optimal effects. asp also enhances the gene expressions of il-2 and ifn-γ.89 the anti-tumor activity of asp is revealed in that asp can significantly inhibit the proliferation of hela cells and lung cancer cells. it is believed to nourish the blood, restore the body’s natural balance, and serve as a female tonic for a number of gynecological conditions, including amenorrhea. a. sinensis is known to have spasmolytic effects on the uterus, specifically in the treatment of dysmenorrhea.
additional research is needed to better understand the benefits and potential cautions in use. it is important, even when there has been a resection and anastomosis of the bowel, to re-establish normal bowel function. qi-regulating herbs help to re-establish the channels and the normal flow of spleen qi upward, stomach qi downward, and the liver/gallbladder qi in a circular direction. after surgery it is important to prevent the formation of adhesions that are a form of blood stasis and also contribute to local blood stasis. the remaining herbs direct the qi of the formula to the phlegm and are antineoplastic.
angelicae pubescentis radix (apr) is a widely used antirheumatic chinese medicinal herb known as “duhuo” in china. it has the effects of in traditional chinese medicine, angelica roots is used for tonifying, replenishing, and invigorating blood as well as relieving pain, lubricating the intestine in chinese medicine it is used to tonify the blood for those who are pale or have dry and brittle hair and nails. it is commonly prescribed for women who suffer, angelica root benefits, angelica root benefits, angelica archangelica homeopathy, angelica root benefits for skin, angelica root taste.
radix angelica sinensis, the dried root of angelica sinensis (danggui), is a herb used in chinese medicine to enrich blood, promote blood circulation and modulate the immune system. it is also used to treat chronic constipation of the elderly and debilitated as well as menstrual disorders. a. sinensis may increase your blood pressure, cause heart problems, and interact with blood thinners. additionally, plants in the angelica genus may interact with drugs that carry a grapefruit warning. dong quai (angelica sinensis) root has been used for more than one thousand years as a spice, tonic, and medicine in china, korea, and japan. in traditional chinese medicine (tcm), angelica roots are plants that belong to the ‘warm/acrid herbs that release the exterior’ category. herbs that release dong quai (angelica sinensis) is a plant that has been used for a variety of conditions, with little evidence. it may be unsafe when too much is consumed., dang gui side effects, dang gui estrogen, angelica root side effects, angelica root benefits for fertility, angelica root pregnancy, angelica root benefits for hair, angelica sinensis common name, angelica herb, radix angelicae pubescentis, dang gui benefits.
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