participants were from different ethnic backgrounds with the majority of chinese origin. the quality of the evidence ranged from very low to moderate; there is a need for well-designed randomised controlled studies. it offers a clear and systematic approach to the management of menopausal symptoms (scheid 2007). this is one of the underpinning theoretical constructs of tcm and a number of complementary therapies. a review of the literature of 485 clinical studies (liu 2008) in 2008 reported that 185 herbs were used to treat menopausal symptoms. the authors concluded that the formula could produce a reduction in frequency of vasomotor symptoms and that overall quality of life was also improved. for frequency, the daily number of episodes is recorded as one point. improvement in menopausal symptoms: this method was reported in some of the included chinese studies. data collection and analysis were conducted in accordance with the cochrane handbook for systematic reviews of interventions (higgins 2011). discrepancies between the number of participants enrolled and number for whom outcomes were reported were noted in the characteristics of included studies table. an increase in the odds of an outcome was displayed to the right of the centre line while a decrease in the odds of an outcome was displayed to the left of the centre line. the studies included 2902 women with a total of 1499 participants in the intervention groups and 1403 in the control groups. however there was a tendency to use certain herbs in menopause research, for example, the following 11 herbs were identified as the most frequently tested.
however, non blinding occurred mainly in the studies in which chm was compared against ht, and we did not consider that blinding was likely to influence findings for the objective secondary outcomes such as changes in levels of the hormones and lipids; adverse effects were also unlikely to be affected. only one study reported this outcome (zhong 2013), with a difference between the chm group and the placebo, in favour of the chm group (md −0.70 points, 95% ci−1.00 to −0.40; 1 rct, 108 women (analysis 1.1; figure 4). this reports overall scores of hot flushes (including frequency and severity), which were measured monthly in a diary. when menopausal symptoms were compared by using the ki and menqol, there was some suggestion of improvement in the three studies, however there was little evidence of a difference between the groups in the fourth study, which used the hfdri. no study reported the qol specifically in the comparison of chm versus placebo. a total of 23 adverse events were reported in the 463 women assigned to chm and 24 adverse events in the 401 women assigned to ht. data were assessed and findings were reported in line with the rigorous scientific research ideologies and consideration of the fundamental philosophies employed in traditional chinese medicine (tcm). meta-analysis of the pooled data found chm was no better than placebo for vasomotor symptoms measured by frequency and severity of daily hot flushes, and overall scores of vasomotor symptoms by a specific questionnaire. the objective of this review was to evaluate the effectiveness and safety of chm in perimenopausal and postmenopausal women using the same research methods across the included studies. the quality of the evidence for chm for menopausal symptoms was affected by inadequate reporting of study methods. based on the findings, this review was unable to draw firm conclusions about the effectiveness and safety of chm for menopausal symptoms due to inadequate quality of the research evidence. when the review was undertaken, there were a number of comparisons in variation noted. no details are given on other outcome measurements although it is mentioned that two sets of data were collected before and after the intervention
seven english and chinese databases were searched for studies from respective inceptions to february 2019. randomized controlled trials investigating the clinical effects and safety of chm formulae on mhf were considered for inclusion. this study aimed to conduct a systematic review which offers a comprehensive evaluation of the therapeutic effects and safety of chm for mhf and identify the most commonly used chm formulae and individual herbs for mhf. studies involving inappropriate comparison leading to the effects of chm formulae could not be determined were also excluded. in this review, the primary outcome measures were the subjective feelings of mhf including effectiveness rate, frequency, severity and score (i.e. three were not included in the meta analysis due to lack of data [27, 29, 32]. the characteristics of included studies are summarized in table 1 and details of ingredients of chm formulae are provided in s2 table.
thus, only data from the treatment group of combined formula and the control group in this study were analyzed in this review. three different measures of mhf relief were used in the included studies, namely severity, frequency and score. five studies indicated that no aes were reported in the chm group [18, 20, 21, 26, 36]. this study aimed to evaluate the therapeutic effects and safety of chm formulae. although the majority of the studies measured mhf relief and qol as the primary outcomes, different measures were used across studies, which led to difficulty in data synthesis. due to the high variations of investigated chm formulae in the included studies, future rigorously conducted studies investigating on a specific non-modified chm formula for the management of mhf are recommended.
dang gui (radix angelicae sinensis), a commonly used chinese herb, was most frequently cited. this herb has traditionally been used to treat the most popularly studied formula was kun tai capsule and the most frequently prescribed herb was bai shao (paeoniae radix alba, paeonia two herbs for menopause formulas are frequently used: three immortals, which addresses the general patterns associated with the menopausal, chinese herbs for menopause weight gain, chinese herbs for menopause hot flashes, chinese herbal tea for menopause, chinese herbal tea for menopause, chinese soup for menopause.
the authors believe that chinese herbal medicine might relieve hot flashes due to estrogen-like effects. for instance, some of the herbs that the researchers used in the trials, including bai shao, dang gui, zhi mu, chai hu, huang qin, and yin yang huo, contain phytoestrogens. zhi bai di huang wan/temper fire: this is probably the most popular chinese herbal formula for hot flashes. it is considered a kidney yin tonic that clears fire vegetables: fennel (chinese medicine practitioners prescribe this to help regulate the menstrual cycle), beetroot, asparagus, garlic, kale, alternative medicine, including food therapy, is a viable option for managing menopause symptoms. what causes this disparity between menopausal women in the, chinese herbs for night sweats, ancient remedies for menopause.
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