the system of herbal medicine that developed in china differs in several significant ways from european herbal medicine. in neighboring japan, a variation of the tchm system known as kampo has become popular, and the japanese health ministry has approved many kampo remedies for medical use. the herbal formulas used in tchm consist of four categories of herbs: ministerial, deputy, assistant, and envoy. in the west, herbal medicine is part of folk medicine. in the traditional system of chinese herbal medicine, herbal formulas can be used to treat virtually any condition. the herbal combination shosaiko-to (minor bupleurum) has been approved as a treatment for chronic hepatitis by the japanese health ministry, and it enjoys wide use in that country and elsewhere. in a double-blind, placebo-controlled trial, 220 people with allergic rhinitis were given either placebo or the kampo remedy sho-seiryu-to for a period of 2 weeks. the kampo remedy shakuyaku-kanzo-to is a combination of peony root and licorice , commonly used for the treatment of muscle spasms in general. in a 12-week, double-blind study, a different traditional chinese herbal formula also failed to prove more effective than placebo for treatment of eczema. a double-blind study performed in hong kong evaluated the potential benefits in cancer chemotherapy of personalized herbal formulas designed according to the principles of traditional chinese herbal medicine. in a 2011 review of 14 randomized trials involving 1,316 women, the addition of chinese herbal medicine to the prescription medication clomiphene (used to induce ovulation) was associated with increased pregnancy rates. a review of 17 trials found that there is limited evidence to support the use of traditional chinese herbal preparations for the common cold . according to tchm theory, the various herbs in a formula balance and moderate each other. 68 another set of potential problems arises from the fact that chinese herbal medicine does not restrict itself to plant products with subtle effects. 37 in another episode, 8 out of 11 chinese herbal creams sold in the united kingdom for the treatment of eczema were found to contain strong pharmaceutical steroids.
chinese herbal medicine and interferon in the treatment of chronic hepatitis b: a meta-analysis of randomized, controlled trials. the chinese herbal formulation biminne in management of perennial allergic rhinitis: a randomized, double-blind, placebo-controlled, 12-week clinical trial. treatment of asthma patients with herbal medicine tj-96: a randomized controlled trial. a controlled trial of traditional chinese herbal medicine in chinese patients with recalcitrant atopic dermatitis. chinese herbal medicines in the treatment of acute respiratory infections: a review of randomised and controlled clinical trials. adulteration of chinese herbal medicines with synthetic drugs: a systematic review. a randomized trial of chinese herbal medicines for the treatment of symptomatic hepatitis c. arch intern med. a randomized, observer-blind, controlled trial of the traditional chinese medicine yi-gan san for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients. chinese herbal recipe versus diclofenac in symptomatic treatment of osteoarthritis of the knee: a randomized controlled trial [isrctn70292892]. chinese herbal medicine and chemotherapy in the treatment of hepatocellular carcinoma: a meta-analysis of randomized controlled trials. effectiveness of a chinese herbal medicine preparation in the treatment of cough in uncomplicated upper respiratory tract infection: a randomised double-blind, placebo-controlled trial. efficacy and tolerability of a chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study. a meta-analysis of chinese herbal medicine in treatment of managed withdrawal from heroin. the beneficial effects of the herbal medicine free and easy wanderer plus (fewp) and fluoxetine on post-stroke depression. oseltamivir compared with the chinese traditional therapy maxingshigan-yinqiaosan in the treatment of h1n1 influenza: a randomized trial.
traditional chinese medicine (tcm) has been practiced over thousands of years in china and other asian countries for the treatment and symptom management of a wide range of medical conditions. it is accessible by drug discovery researchers worldwide (academic and non-profit organizations) to investigate tcm plants as potential sources of agents for the treatment of human disease. requests for the nci library of tcm plant extracts will be accepted from research organizations and individual investigators in the form of a brief proposal (up to 5 pages) formatted as follows: requests will normally be reviewed by staff of the nci division of cancer treatment and diagnosis (dctd).
the committee to review applications for access to the nci library of tcm plant extracts will accept and review proposals on a continuing basis. carol haggerty natural products branch developmental therapeutics program division of cancer treatment and diagnosis national cancer institute riverside five, suite 400, room 4101 p. o. box b frederick, md, 21702 barry r. o’keefe, ph.d. chief, natural products branch, developmental therapeutics program division of cancer treatment and diagnosis nci bldg. in botany from michigan state university, and a ph.d. in pharmacognosy from the university of illinois at chicago in 1993. in 1994 he joined the national cancer institute’s laboratory of drug discovery research and development to study novel proteins from natural products extracts.
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