this study aimed to investigate the prevalence of herbal medicine use among cancer patients in the west midlands, and determine the characteristics predicting herbal medicine use. the aim of this study was to investigate the prevalence of herbal medicine use among people with cancer in the west midlands, and to determine the sociodemographic and cancer-related characteristics that may predict herbal medicine use within this group. survey content was informed by the findings of a systematic review of the literature relating to herbal medicine use by cancer patients in the united kingdom (gratus et al, 2009a). as the survey population was identified from the records of one hospital only, the survey was repeated on a smaller scale at another hospital in birmingham (541 patients mailed), in order to validate the rates of herbal medicine use identified from survey respondents treated at uhc&w and assess the wider generalisability of the findings.
patients who were >4 years since diagnosis had the highest rate of use (n=64; 24.1%), and patients with female genital cancers and breast cancer were most likely to be herbal medicine users (n=28; 24.6% vs n=133; 22.7%). patients were also given the opportunity to cite the use of other herbal medicines not detailed in the pre-coded list. in common with other studies, we found that women with breast cancer are particularly likely to use herbal medicines, as are women with genital cancers, although in the multivariate analyses, cancer site was not a significant predictor of herbal medicine use. it is possible that this group may have been more likely to use herbal medicines to help them cope with the stress they were experiencing, and thus we have under-estimated the overall prevalence of herbal medicine use by cancer patients. ethical approval for this study was obtained from the birmingham east, north and solihull research ethics committee (rec), ref 08/h1206/153.
a substantial number of patients with cancer receive chemotherapy or chemoradiotherapy and benefit from treatment with anticancer drugs (desantis et al., 2014). the ghrelin receptor is expressed in the same neurons and is thus considered to stimulate food intake by activating the npy/agrp neurons (nakazato et al., 2001). hangeshashinto is composed of seven herbs and is often used in japan to treat diarrhea and acute gastroenteritis (kase et al., 1997). (2015) investigated the effect of hangeshashinto for chemoradiation-induced mucositis in head and neck cancer patients, and hangeshashito was associated with a significantly improved rate of completion of chemoradiation with cisplatin. (2013) evaluated the efficacy of goshajinkigan for oxaliplatin-induced neuropathy in patients with colorectal cancer and demonstrated that goshajinkigan prevented exacerbation of neuropathy. j. oncol. identification of the metabolites of irinotecan, a new derivative of camptothecin, in rat bile and its biliary excretion. ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. the role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. systematic review of agents for the management of gastrointestinal mucositis in cancer patients. prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: american society of clinical oncology clinical practice guideline. the oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin—the aprepitant protocol 052 study group. preventive effects of hange-shashin-to on irinotecan hydrochloride-caused diarrhea and its relevance to the colonic prostaglandin e2 and water absorption in the rat.
phase 1/2 clinical study of irinotecan and oral s-1 (iris) in patients with advanced gastric cancer. topical application of hangeshashinto (tj-14) in the treatment of chemotherapy-induced oral mucositis. efficacy of goshajinkigan for peripheral neurotoxicity of oxaliplatin in patients with advanced or recurrent colorectal cancer. systematic review of basic oral care for the management of oral mucositis in cancer patients. a role for ghrelin in the central regulation of feeding. doi: 10.1007/s10147-010-0183-1 ohno, t., yanai, m., ando, h., toyomasu, y., ogawa, a., morita, h., et al. guideline update for mascc and esmo in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the perugia consensus conference. protective effects of kampo medicines and baicalin against intestinal toxicity of a new anticancer camptothecin derivative, irinotecan hydrochloride (cpt-11), in rats. the effects of goshajinkigan, a herbal medicine, on subjective symptoms and vibratory threshold in patients with diabetic neuropathy. doi: 10.1016/j.diabres.2004.11.017 ushio, s., egashira, n., sada, h., kawashiri, t., shirahama, m., masuguchi, k., et al. doi: 10.1007/s00383-003-1053-y yakabi, k., kurosawa, s., tamai, m., yuzurihara, m., nahata, m., ohno, s., et al. 2013, 139740. doi: 10.1155/2013/139740 citation: ohnishi s and takeda h (2015) herbal medicines for the treatment of cancer chemotherapy-induced side effects. the use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice.
research into herbal medicine for cancer. there is no reliable evidence from human studies that herbal remedies can treat, prevent or cure any type of cancer. there is no reliable scientific evidence that herbal remedies alone can cure or treat cancer. however, some plant extracts have been found to have anti-cancer a number of herbal supplements including echinacea, kava, grape seed, and st john’s wort (hypericum perforatum) are also considered to be inducers of cyp , .
breast cancer patients were the most likely to use each of the specified herbs, constituting 100% of users of agnus castus (vitex agnus castus), dong quai ( accumulating evidence suggests that japanese herbal medicines, called kampo, have beneficial effects on cancer chemotherapy-induced side for example, american ginseng and astragalus root used in traditional chinese medicine may help reduce some side effects of chemotherapy, such, .
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