several in vitro and in vivo studied conducted to evaluate cytotoxic effects of quercetin on ovarian cancer. the various molecular and genetic alterations of these types of ovarian cancer as well as their different responses to therapies lead to a challenge in design a common treatment strategy . several studies have investigated cytotoxic effects of quercetin on ovarian cancer cells both in vitro and in vivo. thus, in this review, we focused on chemo-preventive and curative attitude of quercetin for ovarian cancer and summarize some of the most recent findings which regard the possible molecular mechanisms by which this natural compound inhibits this cancer. the dynamic alteration in cytokines of ascites has been indicated in a recent study in which ascites and plasma samples of advanced epithelial ovarian cancer showed a remarkable change in cytokines and inflammatory molecules . moreover, increased nitrosylation of caspase-3 which leads to a significant reduction in the activity of caspase-3 was seen in ovarian tumors.
quercetin is also observed to arrest cell cycle in several types of cancers. recently, the effects of quercetin on ovarian cancer have been interesting for many researchers. this form of quercetin significantly inhibited growth of ovarian cancer cells both in vitro and in xenograft ovarian cancer mice. the cell cycle modulation and cytotoxic effect of quercetin on ovarian cancer cells was investigated in an in vitro study.  evaluated the effect of quercetin on sensitization of ovarian cancer cells to trail. za contributed in conception, design and drafting of the manuscript.
“whenever i felt nauseous or exhausted, i would close my eyes and visualize the drugs as little smart bombs that traveled around my body to find and kill my cancer cells,” says peltier, a retired attorney in houston. sometimes she pictures an army of women soldiers roaming through her body, attacking stray cancer cells. “it’s given me confidence that i can handle anything, even the unknown.” research suggests that at least half of all women diagnosed with ovarian cancer turn to complementary therapies. the key, she stresses, is for people to work closely with their health care team to make sure that any therapies they use don’t interfere with medical treatments like chemotherapy. “they can be very beneficial to combat side effects of cancer such as fatigue, anxiety and pain,” says larissa meyer, md, an associate professor of gynecologic oncology at the md anderson cancer center in houston. it may help with chemotherapy side effects such as nausea, fatigue, and numbness in the hands and feet, says meyer.
it isn’t recommended that you take any sort of supplement during chemotherapy without checking with your doctor, as it may interfere with the treatment, stresses meyer. if your cancer center has an integrative medicine clinic, talk to someone there as well. another study of women with ovarian or breast cancer found that 10 weekly yoga classes lowered levels of fatigue, depression, and anxiety in patients. “i often counsel patients to use these sorts of exercise to help them relax as they wait for chemotherapy treatments, or for the results of an imaging test or scan,” she says. even something that seems totally safe could interfere with your cancer treatment. it will work with you to find safe and effective therapies. your doctor will be happy to answer your questions and concerns so you can get the best possible care.
quercetin is one of the phytochemicals that exists extensively in daily foods. wide evidences revealed that quercetin is able to inhibit various quercetin. this substance is found naturally in fruits and vegetables such as apples, onions, red grapes, cherries, raspberries, and citrus researchers from the university of michigan comprehensive cancer center have found that ginger not only kills cancer cells, it also prevents, .
ginger root is an outstanding food for annihilating ovarian cancer cells. when ginger powder is dissolved in a solution containing ovarian lavender oil is promoted to reduce stress, anxiety, insomnia, and muscle tension. inhaled peppermint and ginger oil may help to reduce chemotherapy-related quercetin is one of the phytochemicals that exists extensively in daily foods. wide evidences revealed that quercetin is able to inhibit various, .
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