this may be the case with thymol, a compound found in several plants, including thyme, oregano, rosemary and bay leaves. due to its medicinal properties, thymol is already an ingredient in a leading mouthwash, cosmetics and other products. in the lab, dr. gonzales’s team found that thymol was effective in preventing the proliferation of oral cancer cells. in animal models of human oral cancer, thymol proved to be effective as an anti-tumor agent. “we show that thymol induces mitochondrial dysfunction and cell death, and it may be effective against several types of cancer,” she said.
ut health san antonio has a patent on a thymol mouth rinse to prevent oral cancer and on its mechanism of action to use as a treatment for oral cancer. dr. gonzales hopes to conduct human clinical trials in the future. the university of texas health science center at san antonio, also called ut health san antonio, is a leading academic health center with a mission to make lives better through excellence in advanced academics, life-saving research and comprehensive clinical care including health, dental and cancer services. the content on this website is intended to be used for informational purposes only. consult a health care provider if you are in need of treatment.
the best effect of the combinations was seen for cinnamon-saffron after both 24 and 48 hours and the four herbs combination after 48 hours. hence, the need for new medicines has led to seeking anti-cancer effects in fruits and vegetables (gutheil et al., 2012). recent studies have confirmed the anti-cancer effect of eugenol against various cancer cell lines in various animal models. hence, the present study was performed to quantitatively assess the anti-cancer effect of curcumin, ginger, saffron, and cinnamon per se and in combination on a cell line of oral squamous cell carcinoma.
similarly, the lowest effective concentration of curcumin after 48 hours was observed in 108 mg/ml and the highest was in 217 mg/ml (figure1). the maximum impact (100%) of saffron was achieved in 10 mg/ml and the saffron ic30 after 48 hours was 1.9 mg/ml (figure1). consistently, we reported the anti-cancer effect of ginger on oscc cell line as it was ranked third after saffron and cinnamon. the present study showed that cinnamon had the highest anti-cancer effect after saffron; the minimum effective concentration of cinnamon on oscc was 5 mg/ml in 24 and 48 hours assessment. the laboratory procedures were all performed in school of pharmacy and institute for cancer research, sums, shiraz-iran, to which appreciations are expressed.
spirulina, selenium, green tea (egcg), neem, tomatoes (lycopene), turmeric (curcumin), and some medicinal mushrooms are also used as gonzales’s team found that thymol was effective in preventing the proliferation of oral cancer cells. in animal models of human oral cancer, this study investigated the anti-cancer effects of four medicinal herbs including curcumin, saffron, ginger, and cinnamon on oscc. the findings, .
in december, the academy of general dentistry reported that a new study had found that simply swishing green tea around the mouth halts the growth of new oral spirulina, selenium, green tea (egcg), neem, tomatoes (lycopene), turmeric (curcumin), and some medicinal mushrooms are also used as chemopreventive and green tea extract had powerful benefits. in fact, over half of the participants were less likely to develop mouth cancer due to taking green tea, .
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