radix bupleuri, also called “chaihu” in chinese, is derived from the dried roots of bupleurum chinense dc. saikosaponins a and d are commonly used as chemical standards for quality evaluation of radix bupleuri in the current chinese pharmacopoeia and recent publications. according to the chinese pharmacopoeia, radix bupleuri is derived from the dried roots of bupleurum chinense dc. inevitably, this situation will compromise the values of radix bupleuri and even imperil the safety of the consumers. among them, saikosaponins a, c, and d are the major bioactive constituents found in radix bupleuri; however a variety of minor saikosaponins have also been isolated . an overview of the pharmacological studies on radix bupleuriis presented in detail in the following sections. several chinese medicine preparations containing radix bupleuri also have been traditionally used in the treatment of tumors and cancer.
a novel in situ gel system for nasal delivery of the essential oil from radix bupleuri was prepared. the results showed that both raw and processed radix bupleuri showed liver protective effects against ccl4 induced liver injury, and the vinegar-baked radix bupleuri exerted better effects than that of raw radix bupleuri . the results indicated that radix bupleuri significantly increased the amplitude of spontaneous activity of lymphatic vessels in a concentration-dependent manner, and the mechanisms of this effect seem to be independent of endothelial function . radix bupleuri was shown to be the inhibitor of β-glucuronidase. however, the toxic effects of radix bupleuri in clinical applications have been gradually reported. furthermore, the pharmacological effects of only a few of the ingredients, such as saikosaponins, flavonoids, and the essential oils, have been investigated. in conclusion, this review summarized the traditional uses, botany, phytochemistry, pharmacology, and toxicology of radix bupleuri.
they are used together to treat excessive-heat in the stomach. they are used to treat qi constraint in the middle jiao and hidden fire in the spleen. the chai hu circulates the qi of the liver and also lifts the yang. as it also enters the gall bladder meridian, it is able to regulate the function of the liver and gall bladder. chai hu is a pungent and neutral herb and it is the strongest herb of the three for dispersing the liver-qi.
analysis of the hormones and sperm were normal. ge gen, sheng ma and chai hu all have the functions of releasing the exterior, and dispersing and lifting the yang-qi. it is used to hasten recovery from measles when the expression of the rash is incomplete. it is the most commonly used herb to treat stress, irritability, resentment, depression and other mental and emotional disorders due to stagnation of the liver-qi. it is referred to as xiao-chai-hu-tang in china or shosaiko-to in japan and used for hepatic disorders.
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bupleuri radix is often processed into pieces for easy use, but since the 1940s, bupleuri radix injection has been formulated using steam radix bupleuri (chaihu) has been used as a traditional medicine for more than 2000 years in china, japan, korea, and other asian countries. context: radix bupleuri has been used in traditional chinese medicine for over 2000 years with functions of relieving exterior syndrome, clearing heat,, radix angelicae sinensis, radix bupleuri side effects, radix scutellariae, radix glycyrrhizae.
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