the increasing national and international demand for swertia chirayita has led to unscrupulous collection from the wild and adulteration of supplies. in this review, we document the medicinal uses and phytochemical properties of s. chirayita. multi-colored corolla and the presence of nectaries support cross-pollination in s. chirayita. concurrently, a diverse range of in vitro and in vivo test systems has been used to evaluate the pharmacological properties of s. chirayita. there is increasing evidence on the toxicity of crude extracts and isolated compounds from different plant species (koorbanally et al., 2006). lack of comprehensive data on annual harvested and traded plants of s. chirayita is also a major concern. (2014) reported on synthetic seed production and plant regeneration of s. chirayita from somatic embryos. in summary, s. chirayita have been studied extensively in terms of taxonomy, ethnobotany, phytochemistry, biological activities, and conservation. report: analgesic activities of ethanol extract of leaf, stem and their different fractions of swertia chirata. antidiabetic effect of whole plant extract and fractions of swertia chirayita buch.-ham. doi: 10.1055/s-2006-960041 balaraju, k., agastian, p., and ignacimuthu, s. (2009a). assessment of the antiinflammatory effects of swertia chirata in acute and chronic experimental models in male albino rats. doi: 10.1055/s-2006-958124 bhargava, s., rao, p., bhargava, p., and shukla, s. (2009). antipsychotic activity of gentianine.” j. pharm. sem and elemental studies of swertia chirayita: a critically endangered medicinal herb of temperate himalayas. doi: 10.1038/35012241 chatterjee, a., and pakrashi, s. c. (1995). regeneration and characterization of swertia chirata buch. in vitro and in vivo antioxidant effects of the ethanolic extract of swertia chirayita. metabolic discrimination of swertia mussotii and swertia chirayita known as “zangyinchen” in traditional tibetan medicine by (1)h nmr-based metabolomics. doi: 10.1007/s10068-012-0052-y grover, j. k., yadav, s., and vats, v. (2002). antitumor, immunomodulatory and anti-hiv effect of mangiferin, a naturally occurring glucosylxanthone. doi: 10.1016/j.jep.2004.10.020 jeong, y. t., jeong, s. c., hwang, j. s., and kim, j. h. (2015).
doi: 10.1016/s0378-8741(02)00144-7 karan, m., vasisht, k., and handa, s. s. (1999). production of amarogentin in root cultures of swertia chirata. phytochemical composition, antioxidant activity and hplc profiles of swertia species from western ghats. efficient regeneration and antioxidant activity of the endangered species swertia chirayita. j. biol. antimicrobial screening of methanol and aqueous extracts of swertia chirata. evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms. hepatoprotective activity of andrographis paniculata and swertia chirayita. gastroprotective effects of bitter principles isolated from gentian root and swertia herb on experimentally-induced gastric lesions in rats. pant, n., jain, d. c., and bhakuni, r. s. (2000). encapsulation of internode regenerated adventitious shoot buds of indian siris in alginate beads for temporary storage and twofold clonal plant production. in vitro antibacterial screening of swertia chirayita linn. doi: 10.1002/ptr.1436 saha, p., mandal, s., das, a., and das, s. (2006). doi: 10.1016/j.ejps.2014.02.005 saxena, a. m., bajpai, m. b., and mukherjee, s. k. (1991). saxena, a. m., murthy, p. s., and mukherjee, s. k. (1996). antioxidant capacity and total phenolic content of swertia chirayita (roxb. enhancement of in vitro growth of swertia chirayita roxb. the synergistic biologic activity of oleanolic and ursolic acids in complex with hydroxypropyl-γ-cyclodextrin. vaidya, h., goyal, r. k., and cheema, s. k. (2013). antiviral activity of the indian medicinal plant extract, swertia chirata against herpes simplex viruses: a study by in-vitro and molecular approach. influence of phytohormones and medium on the shoot regeneration from the leaf of swertia chirayita buch.-ham. j. doi: 10.1016/j.fitote.2014.11.011 citation: kumar v and van staden j (2016) a review of swertia chirayita (gentianaceae) as a traditional medicinal plant.
the aim of this review is to provide a synthesis of the current state of scientific knowledge on the medicinal uses, phytochemistry, pharmacological activities, safety evaluation as well as the potential role of plant biotechnology in the conservation of swertia chirayita and to highlight its future prospects. in india, 40 species of swertia are recorded (clarke, 1885; kirtikar and basu, 1984), of which, swertia chirayita is considered the most important for its medicinal properties. in this review, we document the medicinal uses and phytochemical properties of s. chirayita. multi-colored corolla and the presence of nectaries support cross-pollination in s. chirayita. concurrently, a diverse range of in vitro and in vivo test systems has been used to evaluate the pharmacological properties of s. chirayita.
however, despite its long history of use in traditional medicine, there is still a lack of scientific information concerning the safety evaluation of s. chirayita. nevertheless, rigorous clinical studies involving different mechanisms are still needed to confirm the safety of s. chirayita in traditional medicine so that it can be used safely and effectively. there are limitations in the use of seed propagation, due to low viability, and low germination percentages (badola and pal, 2002; chandra et al., 2012). in all probability there is a need for clinical trials to establish the efficacy of using s. chirayita in medicine. additionally, in the near future, hairy root technology can be used as a model system and will also provide plant biotechnologists with powerful tools to improve the valuable phytochemicals of s. chirayita. the shaded area represents the natural habitat of swertia chirayita in the himalayan region.
swertia is a genus in the gentian family containing plants sometimes referred to as the felworts. some species bear very showy purple and blue flowers. many members of this genus have medicinal and cultural purposes. swertia chirayita (gentianaceae), a popular medicinal herb indigenous to the temperate himalayas is used in traditional medicine to treat swertia chirayita (gentianaceae), a popular medicinal herb indigenous to the temperate himalayas is used in traditional medicine to treat numerous ailments the medicinal plant s. chirata is continuously being used as a traditional herb. the data indicated its safe and positive effect in the treatment of various, swertia chirata common name, swertia chirata common name, swertia chirata english name, swertia chirata diabetes, swertia chirata scientific name.
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